Cholestatic liver diseases (CLDs) arise from impaired bile secretion or flow, resulting in accumulation of hepatotoxic bile constituents and progressive hepatic injury. Ursodeoxycholic acid (UDCA), a naturally occurring hydrophilic bile acid is a well-established hepatoprotective agent used in the management of multiple cholestatic and hepatocellular disorders. UDCA exerts pleiotropic effects including enhancement of hepatobiliary secretion, expansion of the hydrophilic bile acid pool, stabilisation of hepatocellular membranes and anti-apoptotic, antioxidant and immunomodulatory actions. By shifting bile composition toward less toxic bile acids, UDCA mitigates cholestatic injury, improves biochemical parameters and supports favourable clinical outcomes. However, in recent years, it has been reported that emodin, a Chinese herbal compound, is effective against cholestatic liver injury (CLI). a natural red-orange plant compound found in rhubarb, knotweed, and various traditional herbs. It belongs to a chemical family called anthraquinones, which are ring-shaped carbon compounds produced by plants, molds, and fungi. First, please describe bile acid dynamics during CLI. Additionally, explain the mechanism by which emodin improves bile acid dynamics. Furthermore, the authors state that fecal transplantation is an effective treatment for CLI; describe the indications and mechanisms of action. It is attracting attention as a novel therapeutic approach for various liver diseases—including cholestatic liver injury—by correcting gut microbiota imbalances (dysbiosis). • Normalization of microbiota: Transplanting stool from healthy donors restores microbial diversity and beneficial bacteria. • Reduction of inflammation and fibrosis: Animal experiments and clinical studies have shown that it modulates intestinal immunity and metabolic pathways, thereby alleviating hepatic inflammatory markers and histological damage. • Tool for therapeutic validation: It is also utilized in research (FMT experiments) to verify the hepatoprotective effects of herbal medicines and probiotics (e.g., *Lactobacillus acidophilus*) by demonstrating that their efficacy depends on the gut microbiota. Please describe the timing, indications, and duration of the effects of fecal microbiota transplantation for SLI.